Without the messenger insulin, cells cannot use glucose as fuel, which can lead to them not working properly. In turn, the control center (pancreas) secretes insulin into the blood effectively lowering blood sugar levels. Principal Hormone Effects on the Glucose-Fatty Acid Cycle: Under conditions of CHO stress (lack of CHO's): There is depletion of liver glycogen stores. BBC Bitesize. Deregulation means precisely the opposite and is when a cell makes itself less sensitive to a hormone. The hormonal system uses chemical messengers called hormones, which are carried by the blood and so take time to get around the body. All rights reserved. Bbc Bitesize - National 4 Biology - Maintaining Stable Body Conditions - Revision 5. In addition to its role in controlling blood sugar levels, insulin is also involved in the storage of fat. If you're monitoring your glucose levels for health and optimization reasons, it helps to know the nitty-gritty of the relationship these hormones have. Du Bist Dran Buch, When blood sugar rises in the blood, insulin sends a signal to the liver, muscles and other cells to store the excess glucose . These two hormones have various effects on the body and are produced by various pancreatic cells. Blood glucose levels and obesity Pancreatic receptors are involved in negative feedback control of blood glucose through insulin, glucagon and adrenaline. Pancreatic receptors are involved in negative feedback control of blood glucose through insulin, glucagon and adrenaline. Glycogen is a stored form of glucose. This hormone signals your liver and muscle cells to convert the stored glycogen back into glucose. Glucose homeostasis relies on the balance and interaction between glucose and insulin. This triggers your pancreas to produce glucagon. Your bodys regulation of blood glucose is an amazing metabolic feat. During digestion, this is broken apart into glucose, which absorbed into our bloodstream. In response to a high protein meal, glucagon levels in the blood rise. Glucagon levels are usually not measured or monitored in people with diabetes, but your provider may need to adjust your medication management (and sometimes lifestyle management) to minimize both low and high blood sugar episodes. Healthline Media does not provide medical advice, diagnosis, or treatment. Glucagon is a hormone released from the alpha cells in the pancreas. How glucagon works. Twelve foods that wont raise blood glucose. How our bodies do this is studied in GCSE biology. The liver provides or stimulates the production of glucose using these processes. amount of glucose the cells are able to absorb will be reduced. Hypoglycemia means blood sugar levels are low. Insulin helps your cells take up glucose and use it as energy - or store it for future use. Our teachers and animators come together to make fun \u0026 easy-to-understand videos in Chemistry, Biology, Physics, Maths \u0026 ICT.VISIT us at www.fuseschool.org, where all of our videos are carefully organised into topics and specific orders, and to see what else we have on offer. When a person consumes carbohydrates through foods, their body converts them into glucose, a simple sugar that serves as a vital energy source. Glucose Homeostasis: the balance of insulin and glucagon For most of us, our bodies produce insulin naturally. of glucose, i.e. A person can manage their diabetes by making healthful changes to their diet, exercising frequently, and regularly taking the necessary medications, Almost all foods contain amounts of sugar. as well as the hormones insulin and glucagon. It regulates glucose concentrations in the blood. Why are liver cells able to respond to the hormones insulin and glucagon? utilization is logical: 2) the obligatory requirement by some tissues (i.e. Feedback Loops: Insulin and Glucagon - The Biology Corner They can have problems producing insulin or using insulin effectively. In people with diabetes, glucagon's presence can raise blood glucose levels too high. Known as GLP-1 (glucagon-like peptide-1), it is also found in humans and other animals, where it promotes insulin release, lowering blood glucose levels. Its symptoms include faintness and dizziness, and it can be life threatening. 5-10%; lactate 10-15%). It also comes as a kit, with a syringe, some glucagon powder, and a liquid to mix with it. Insulin and blood glucose Glucose is needed in the blood to supply cells with glucose for respiration. Insulin and glucagon work together in a balance and play a vital role in regulating a persons blood sugar levels. If you have diabetes and are experiencing frequent episodes of low or high blood sugar, its important to contact your healthcare provider. Something went wrong while submitting the form. Obese Individuals: even with prolonged medically 1) Enhances release of glucose from glycogen; 2) Enhances absorption of sugars from intestine. Insulin is an anabolic hormone, meaning that it promotes growth. 1) Enhances release of liver glucose during fasting. liver and muscle cells convert excess glucose to, Structure and function of arteries, capillaries and veins, Pathology of cardiovascular disease (CVD), Religious, moral and philosophical studies. to free fatty acids as fuel. Glucagon is a catabolic hormone, meaning that it breaks down larger molecules. Persistently high levels can cause long-term damage throughout the body. pro-insulin (after) is formed in the ER, and mature insulin is formed in the golgi cleavage. to glucose or fat, with the amino nitrogen going to urea. In some cases, a doctor will recommend insulin for people with type 2 diabetes. Learn what levels should be and the symptoms of high and low blood sugar. These cells then release the glucose into your bloodstream so your other cells can use it for energy. When a persons blood sugar is too high, their pancreas secretes more insulin. measures an individuals ability to maintain glucose homeostasis, Diabetic: can not produce or respond to insulin ratio. In this video, you will learn how the pancreas and liver are involved in controlling blood sugar levels in humans. 10. Homeostasis is the regulation of the internal conditions within cells and whole organisms such as temperature, water, and sugar levels. Insulin lowers your blood sugar levels, and glucagon raises them. Appointments & Locations. Learn about and revise homeostasis, body temperature, blood glucose, diabetes and water balance with GCSE Bitesize Biology. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, What are the side effects of insulin therapy, below 70 milligrams per deciliter (mg/dl), Read more about optimal blood sugar levels here, https://www.cdc.gov/diabetes/basics/symptoms.html, https://www.diabetes.co.uk/diabetes-medication/glucagon-injection-kit.html, https://www.ncbi.nlm.nih.gov/books/NBK534841/, https://diabetes.org/healthy-living/medication-treatments/blood-glucose-testing-and-control, https://www.ncbi.nlm.nih.gov/books/NBK559195/, https://www.ncbi.nlm.nih.gov/books/NBK430900/, https://www.ncbi.nlm.nih.gov/books/NBK560688/, https://www.ncbi.nlm.nih.gov/books/NBK537082/, Cardiovascular health: Insomnia linked to greater risk of heart attack. Ways of giving glucagon include injections or a nasal spray. (n.d.). Its thought to be an autoimmune disorder in which your immune system destroys the cells that make insulin in your pancreas. In this article, we look at nine ways to lower high insulin levels. Find all of our Chemistry videos here: https://www.youtube.com/playlist?list=PLW0gavSzhMlReKGMVfUt6YuNQsO0bqSMVFind all of our Biology videos here: https://www.youtube.com/playlist?list=PLW0gavSzhMlQYSpKryVcEr3ERup5SxHl0Find all of our Physics videos here: https://www.youtube.com/playlist?list=PLW0gavSzhMlTWm6Sr5uN2Uv5TXHiZUq8bFind all of our Maths videos here: https://www.youtube.com/playlist?list=PLW0gavSzhMlTKBNbHH5u1SNnsrOaacKLuInstagram: https://www.instagram.com/fuseschool/Facebook: https://www.facebook.com/fuseschool/Twitter: https://twitter.com/fuseSchoolAccess a deeper Learning Experience in the FuseSchool platform and app: www.fuseschool.orgFollow us: http://www.youtube.com/fuseschoolBefriend us: http://www.facebook.com/fuseschoolThis is an Open Educational Resource. Glucagon prevents your blood sugar from dropping too low. People with Type 2 diabetes may have glucagon levels that are relatively higher than what would be considered normal based on blood glucose levels. Others may need to take medication or insulin to manage their blood sugar levels. of glucose versus fatty acids or ketone bodies". http://armandoh.org/https://www.facebook.com/ArmandoHasudunganSupport me: http://www.patreon.com/armandoInstagram:http://instagram.com/armandohasudunganTwitt. III) : These phase is characterized by events which occur 24 to 72 2005-2023 Healthline Media a Red Ventures Company. Exercise can therefore be a useful way to reduce blood glucose levels and can be particularly useful in people with type 2 diabetes Following exercise, the muscles will try to replenish their stores of glycogen and will therefore take in available glucose from the blood to do so, helping to lower blood glucose over this period. If a persons blood sugar levels fall too low, they may need glucagon. With Nutrisense, youll be able to track your blood glucose levels over time using a CGM, so you can make lifestyle choices that support healthy living. Pancreatic receptors are involved in negative feedback control of blood glucose through insulin, glucagon and adrenaline. As a result, the pancreas may not be able to respond effectively enough to rises in blood glucose. Be specific. When we exercise, our muscles will take advantage of their stored glycogen. A person with diabetes cannot regulate their blood sugar, mainly because the pancreas does not release enough insulin. Practitioners continue to debate the exact glucose targets that should be attained for inpatients;5, 6 however, there is more t Blood sugar regulation biology encyclopedia cells, body. Excess amino acids not needed for protein synthesis are converted These insulins are ideal for preventing blood sugar spikes after you eat. As you can see, the relationship between insulin and glucagon is bidirectional. Negative feedback can be explained with the process of insulin production and release. type 2 diabetes bbc bitesize menu diet. Find support, share experiences and get exclusive member cookbooks, giveaways and freebies. Because of this, theyre more likely to develop frequent low or severely low blood sugars if they take medication that could cause low blood sugars especially synthetic insulin and medications in the class of sulfonylurea. Insulin enables your body to take glucose out of the bloodstream into the cells so that they can use it for energy or store it for later.. After giving glucagon, someone should monitor the person for adverse effects. It is a large gland located behind the stomach. But for Type 1 (T1) diabetics like Ms Marston, insulin comes in clear glass vials, handed over the pharmacy counter each month - if they can . Scribd is the world's largest social reading and publishing site. If an increase in blood glucose the change is detected by cells in the pancreas which releases more insulin and less glucagon into the blood. In cases of prediabetes, where blood sugar levels are, Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. Homeostasis is how the body keeps conditions the same, there are many roles involved in homeostasis one being the regulation of blood sugar. This page was last edited on 30 January 2023, at 05:05. When your blood glucose level falls, for example during exercise when your muscles are using glucose for fuel, your pancreas detects the drop in blood glucose. Role of glucagon in control of blood sugar levels Higher, Coordination and control - The nervous system - AQA, Coordination and control - The human endocrine system - AQA, Sample exam questions - homeostasis and response - AQA, Home Economics: Food and Nutrition (CCEA). Glucagon is a natural hormone your body makes that works with other hormones and bodily functions to control glucose (sugar) levels in your blood. Overall, insulin and glucagon work to control the blood glucose levels. In gestational diabetes, pregnancy-related hormones may interfere with how insulin works. Five distinct membrane receptors (SSTR1-5) for SST are known, and at least two (SSTR2 and SSTR5) have been proposed to regulate pancreatic endocrine function. Glucagon - What is Glucago, Role of Glucago, Glucagon Secretion - Diabetes uptake in muscle and adipose tissue and by promoting glycolysis and glycogenesis The gland called pancreas secrete two hormones and they are primarily responsible to regulate glucose levels in blood. The content of these pages has not been reviewed or Start with our quiz to see how Nutrisense can support your health. The following conditions can affect or be affected by your glucagon function: Depending on the situation and condition, you can experience low and/or high blood sugar from abnormal glucagon levels. Read on to learn more about how they function and what can happen when they dont work the way they should. (2022). Glycogen and Diabetes - Role, Storage, Release & Exercise When a persons blood glucose levels fall, pancreatic cells secrete glucagon, stimulating two processes: gluconeogenesis and glycogenolysis. Tests & diagnosis for gestational diabetes. The glucose-fatty acid cycle is starting to switch its emphasis With type 2 diabetes, your body makes insulin but your cells dont respond to it normally. In type 2 diabetes, individuals produce insulin but their cells are less sensitive to it. The control of blood sugar (glucose) by insulin is a good example of a negative feedback mechanism. The signs and symptoms of low blood sugar include: If youre experiencing these symptoms, its important to eat food with carbohydrates/sugar to treat it and bring your blood sugar levels up. Insulin and glucagon: how do they work? pyruvate, or pentoses for the generation of NADPH for synthetic processes. In blood glucose regulation, the hormone insulin plays a key role. About Insulin: What It Is, How It Works, and More - Healthline Is exercise more effective than medication for depression and anxiety? While other glucagon issues are rare, if youre having symptoms, its essential to figure out the cause. ; Glucagon and insulin interact as part of a negative feedback cycle to control blood glucose (sugar) levels in the body: Like insulin, the target organ for glucagon is also the liver, though it stimulates the opposite process the breakdown of glycogen into glucose. State (Phase I): The well-fed state operates while food is being absorbed In a healthy body, the pancreas will respond to higher levels of blood glucose , such as in response to eating, by releasing insulin which will lower blood glucose levels by prompting the liver and muscles to take up glucose from the blood and store it as glycogen. Olive Oil: Olive oil is rich in healthy fats which do not increase insulin resistance. After meals, your body goes into something called the fed state. Rapid- or short-acting insulin. After a meal the blood sugar level will be elevated due to the absorption of sugars from the digestive tract. We avoid using tertiary references. The most common adverse effect is nausea, but they may also vomit. Its chemical messenger effect is the opposite of insulin. What would you expect to happen if your blood sugar was 120 mg / 100 mL ? 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Too little insulin is a problem usually seen in people with diabetes. The liver lets most of the amino acids pass through, this is When blood sugar rises in the blood, insulin sends a signal to the liver, muscles and other cells to store the excess glucose. Empty reply does not make any sense for the end user. Protein conservation is achieved and glucose homeostasis is the brain. Hormones are responsible for key homeostatic processes including control of blood glucose levels and control of blood pressure. through negative effects on glucose transport as well as on the activities of Pancreas and insulin: An Overview - MyDr.com.au If you have type 1 diabetes, your pancreas does not produce insulin or does not produce enough insulin. Heart failure: Could a low sodium diet sometimes do more harm than good? 1) Enhances release of glucose from glycogen; 2) Enhances release of fatty acids from adipose tissue. Glucagon often causes vomiting, so when it is used the person should be kept on his/her . the most glucose (75%) with gluconeogenesis providing the remainder (alanine 6. They can run some tests to see if the cause is an issue with your bodys glucagon or something else. Proteins must therefore by hydrolyzed within muscle to produce Disclaimer: The views and opinions expressed on unofficial pages of California State Insulin and glucagon help manage blood sugar levels. It is produced from proglucagon . Prediabetes your chance to prevent type 2 diabetes. 1) Enhances release of cortisol; 2) Enhances release of fatty acids from adipose tissue. 2. the c-peptide is cleaved off to yield the active hormone. People with type 1 diabetes need to take supplemental insulin to prevent their blood sugar levels from becoming too high. even after three months. If a decrease in blood glucose, the change is detected by cells in the pancreas. Blood sugar regulation is the process by which the levels of blood sugar, the common name for glucose dissolved in blood plasma, are maintained by the body within a narrow range.This tight regulation is referred to as glucose homeostasis.Insulin, which lowers blood sugar, and glucagon, which raises it, are the most well known of the hormones involved, but more recent discoveries of other . Insulin is the key that allows your body to transport glucose and use it or store it as energy., First, it allows your cells to use glucose for immediate energy. Find support, ask questions and share your experiences. of glucagon from the pancreas to promote glucose production. When glucose levels drop, glucagon acts on the liver to initiate gluconeogenesis and glycogenolysis. pre-insulin is a signal peptide, which targets a protein for secretion. Glucagon is a catabolic hormone, meaning that it breaks down larger molecules. In general, Researchers say spinal cord stimulation treatment is showing promise in helping relieve some of the pain caused by diabetic neuropathy, Researchers say 80% of people with type 2 diabetes who are eligible for one of two types of treatments, including Ozempic, aren't getting it, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. In type 2 diabetes, the body can still make insulin, but it may not make enough, and/or insulin resistance has developed. Glycogen plays an important role in keeping our muscles fuelled for exercise. From this the body will then respond to produce more . Fatty acids are mobilized from adipose and their rate Ready to take the first step? Your blood sugar levels can significantly impact how your body feels and functions. Pyruvate derived from glucose can be used for lipogenesis. Insulin: secreted by the pancreas in response to elevated In addition to diabetes, possible causes of high blood sugar include: People with high blood sugar may not notice symptoms until complications appear. It is a large multi-branched polymer of glucose which is accumulated in response to insulin and broken down into glucose in response to glucagon. Is the ketogenic diet right for autoimmune conditions? Insulin helps cells absorb glucose in your bloodstream so the levels of glucose don't get too . oxidation of this fuel. Insulin is a hormone which helps to control sugar levels and Year 10 and Year 11 pupils need to know how. The difference is in how these hormones contribute to blood sugar regulation. They are both secreted inresponse to blood sugar levels, but inopposite fashion! Insulin and glucagon are the two hormones involved in controlling blood sugar levels in individuals. Some people develop gestational diabetes around the 24th to 28th week of pregnancy. Instead, it remains in your bloodstream, leading to high blood sugar levels and symptoms of diabetes., In comparison, low insulin and glucagon levels can also cause health problems.. This balance helps provide sufficient energy to the cells while preventing damage that can result from consistently high blood sugar levels. The main function of the pancreas is to maintain healthy blood sugar levels. Insulin Basics: How Insulin Helps Control Blood Glucose Levels. If your body doesnt make enough insulin, it can cause your blood sugar levels to rise. The second messenger model. Hormones produce an effect on specific target organs in the body. The cells respond by secreting glucagon; The cells respond by stopping the secretion of insulin; The decrease in blood insulin concentration reduces the use of glucose by liver and muscle cells; Glucagon (the first messenger) binds to receptors in the . They are both secreted in response to blood sugar levels, but in opposite fashion. hours after the last meal. NHS approved education and behaviour change app for people with type 2 diabetes, prediabetes, obesity. Glucagon is usually released in a fasted state and during fight or flight moments. Last reviewed by a Cleveland Clinic medical professional on 01/03/2022. However, the body does not use all of this glucose at once. The alpha cells in your pancreas make glucagon and release it in response to a drop in blood sugar, prolonged fasting, exercise and protein-rich meals. Both enzymes are secreted by the pancreas. maintain blood glucose. In more severe circumstances, it is treated by injection or infusion of glucagon. Glucose is one of the vital sources of energy. [7] Insulin also provides signals to several other body systems, and is the chief regulator of metabolic control in humans. In blood glucose regulation, the hormone insulin plays a key role. Doctors may also use glucagon when diagnosing problems with the digestive system. Insulin allows your body to use glucose for energy. Develop healthier lifestyle habits with our helpful tips, and more! You can learn more about how we ensure our content is accurate and current by reading our. Insulin and glucagon are instrumental in the regulation of blood glucose levels, allowing cells to receive proper nutrients. 1) Suppresses glucagon release from cells (acts locally); 2) Suppresses release of Insulin, Pituitary tropic hormones. In gluconeogenesis, the liver produces glucose from the byproducts of other processes. From the liver, it enters the bloodstream. Glucose Homeostasis and Starvation. This chart breaks down the types of insulin, their duration, and the different brands, Diabetes occurs when your body is unable to use its natural insulin properly. In these scenarios, glucagon tells your liver and muscle cells to break down stored glycogen back into glucose. Show replies Hide replies. Elevated levels of plasma fatty acids increase muscle - Flashcards come in decks. Examine the graphic below to understand how this feedback loop works. Insulin is a hormone produced by the pancreas which regulates glucose concentrations in the blood. Insulin and Glucagon: How They Impact Blood Sugar - Greatist What are the different types of diabetes? Glycogen is a stored form of glucose (sugar). Blood sugar regulation is the process by which the levels of blood sugar, the common name for glucose dissolved in blood plasma, are maintained by the body within a narrow range. It is injected into the muscle and signals the liver to release stored sugar that will raise blood sugars. Ahvaz Wetter Sommer, Examine the graphic below to understand how this feedback loop works. What is the normal level of glucose in the blood? Explain how the thermostat in your house uses a negative feedback system to maintain your home's temperature. Insulin and glucagon are hormones that help to regulate blood sugar levels. Synthetic glucagon triggers your liver to release stored glucose, which then raises blood sugar. Why is this called a "set point.". Before meals, the target blood sugar range is less than 95 mg/dL. How do you think they would need to treat low blood sugar? The BBC Bitesize Revision app helps you study for your GCSEs, TGAU, Nationals or Highers with free flashcards and revision guides from the BBC. Check out Joey's Spreads: http://bit.ly/3a5nyxuThank you for watching! They work opposite of each other, but also work together. A persons blood sugar levels vary throughout the day, but insulin and glucagon keep them within a healthy range overall. 9. Where does the glucose that is released into the blood ultimately end up (2 places)? Odds are if they charge less for self-pay they will charge the insurance less (its Diabetes Type 1 And 2 Bbc Bitesize not a foolproof method though.) Milwaukee School of Engineering's Center for BioMolecular Modeling discusses the role of the protein insulin in the regulation of glucose in the bloodstream. tissues begin to switch to fatty acids. Glucagon has an opposite (antagonistic) effect to insulin. nhs.uk/conditions/type-1-diabetes/living-with-type-1-diabetes/avoiding-complications/, cdc.gov/diabetes/basics/insulin-resistance.html, endocrine.org/patient-engagement/endocrine-library/hormones-and-endocrine-function/pancreas-hormones, niddk.nih.gov/health-information/diabetes/overview/what-is-diabetes/gestational/tests-diagnosis, Helping You Understand Normal Blood Sugar Levels, 14 Natural Ways to Improve Your Insulin Sensitivity, Insulin Chart: What You Need to Know About Insulin Types and Timing, Everything You Need to Know About Insulin. BBC Bitesize - Revision on the App Store Once blood sugar levels reach homeostasis, the pancreas stops releasing insulin. Glucagon interacts with the liver to increase blood sugar, while insulin reduces blood sugar by helping the cells use glucose. Last medically reviewed on September 11, 2022. Insulin reduces the bodys blood sugar levels and provides cells with glucose for energy by helping cells absorb glucose. The liver stores glucose to power cells during periods of low blood sugar. Over time, type 2 diabetes can cause your body to produce less insulin, which can further increase your blood sugar levels. causes of type 2 diabetes bbc bitesize on insulin ( dinner) | causes of type 2 diabetes bbc bitesize factshow to causes of type 2 diabetes bbc bitesize for Glucagon can also be used. Your pancreas is a glandular organ in your abdomen that secretes several enzymes to aid in digestion and several hormones, including glucagon and insulin. If you treat your diabetes with insulin, make sure you have emergency glucagon on hand in case you experience a severe low blood sugar episode. The rise in blood sugar stimulates the pancreas to release insulin. Glucose is a type of sugar found in many carbohydrates. Glucagon helps your body make glucose from other sources, such as amino acids. Hormones are chemical messengers. 3. especially important for certain essential amino acids needed by all tissues The same response also occurs when you consume foods and drinks high in sugar such as sweets, cakes, and fizzy drinks.When your blood glucose level drops, such as when you are hungry, the pancreas secretes a hormone called glucagon. To help you revise we've created this quiz for AQA's Unit 3. People can take insulin in various ways, such as pre-loaded syringes, pens, or pumps. Glucagon production issues outside diabetes are uncommon, and some are rare. Glucagon helps blood glucose levels rise back up in multiple ways, including: If your blood glucose levels trend higher, your pancreas releases insulin to bring it back into range. to maintain blood glucose. This can be achieved through diet, lifestyle changes, supplements, and medication. Glucose / Fatty Acid / Ketone Body Cycle: "explains the reciprocal relationship between the oxidation Blood sugar regulation - Wikipedia What cells release insulin? Submit . If a persons body cannot maintain this balance, diabetes and other conditions can result. You can both ask and answer questions, and teachers will get back to you.These videos can be used in a flipped classroom model or as a revision aid. What is negative feedback in biology? 7. Sign in, choose your GCSE subjects and see content that's tailored for you. (2021). The human cost of insulin in America - BBC News 50-60% of glucose is consumed by the brain. Insulin and Glucagon | Physiology | Biology | FuseSchoolIn this lesson, you will learn about how your blood glucose level is regulated (or controlled) by two. Phase IV: Role of Hormones in Response to Starvation and Stress: Ketones play a central role in prolonged starvation, replacing Glucagon is a hormone released from the alpha cells in the pancreas. Based on clues in the graphic, what are the two stimuli? Read about our approach to external linking. Insulin and glucagon work in a cycle. Blood sugar levels should return to safer levels within 1015 minutes. Glycogen is mainly stored in the liver and the muscles and provides the body with a readily available source of energy if blood glucose levels decrease. If you have too much or too little glucose in your blood, it can cause certain symptoms and complications.
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